Sinusitis FAQ

Anyone know what's in it?

Question:

Scott wrote: >>According to http://www.sinofresh.com/content/clinicaloverview.aspx >>Clinical Overview >>What is SinoFresh? > . . . . > So does this mean we can just put some mouthwash (Scope which contains > Cetylpyridinium Chloride) in a spray bottle and have the same affect?

Scope Mouthwash contains alcohol.  You don’t want to put alcohol or any other astringent ingredient up your nose, believe me. — Steven L.

Response:

- Hide quoted text — Show quoted text -NorthShore…@yahoo.com (Mareda) wrote in message <news:b27124f8.0403300457.17d24c0e@posting.google.com>… > entcons…@aol.comnospam (ENTconsult) wrote in message <news:20040329235153.22051.00000311@mb-m22.aol.com>… > > I have been to the web site but couldn’t find any reference as to what is in > > sino fresh. Anyonw know? > > Murray Grossan, M.D. > > http://www.ent-consult.com > Active Ingredients: > Cetylpyridinium chloride 0.5% > Inactive Ingredients: > Benzalkonium chloride, dibasic sodium phosphate, eucalyptus oil, > monobasic sodium phosphate, peppermint oil, polysorbate 80, propylene > glycol, purified water, sodium chloride, sorbitol solution, spearmint > oil and wintergreen oil.

Cetylpyridinium chloride 0.05% Sorry for the correction, Bill

Response:

entcons…@aol.comnospam (ENTconsult) wrote in message <news:20040329235153.22051.00000311@mb-m22.aol.com>… > I have been to the web site but couldn’t find any reference as to what is in > sino fresh. Anyonw know? > Murray Grossan, M.D. > http://www.ent-consult.com

Active Ingredients: Cetylpyridinium chloride 0.5% Inactive Ingredients: Benzalkonium chloride, dibasic sodium phosphate, eucalyptus oil, monobasic sodium phosphate, peppermint oil, polysorbate 80, propylene glycol, purified water, sodium chloride, sorbitol solution, spearmint oil and wintergreen oil.

Response:

- Hide quoted text — Show quoted text -> According to http://www.sinofresh.com/content/clinicaloverview.aspx > Clinical Overview > What is SinoFresh? > SinoFresh is a topical antiseptic nasal spray effective against the molds and > bacteria that are most commonly associated with "Rhinosinusitis."  The need for > an effective topical antimicrobial in nasal and sinus disease is well > documented because, despite extended courses of systemic therapy, the spectrum > of persistent bacteria and fungi in the nose and sinus is extensive.  It is the > persistent extra mucosal colonization that allows these organisms to function > as "living antigens," triggering lgG, lgE, and neutrophil medicated > inflammatory reactions.  No other agent attacks the cause of the inflammatory > response except for the dilutional effect of saline irrigation.  SinoFresh has > been shown to kill these organisms, essentially on contact.  SinoFresh, 1-3 > sprays twice daily, is used as a daily antiseptic nasal hygiene regiment in > patients with chronic nasal and sinus symptoms and in patients who simply > desire a refreshing cleansing of the accessible nasal and sinus mucosa. > What is CPC? > The active ingredient in SinoFresh is a surface active cationic antiseptic, > Cetylpyridinium Chloride (CPC), with antimicrobial activity against bacteria, > fungi, and viruses.  CPC has been used in oral rinse products for over fifty > years and it`s safety has been documented extensively.  It has been formulated > into topical nasal spray, along with moisturizers and mint aromatics, to be > used as a nasal hygiene product.  In Intranasal safety studies to date, and > national chain store distribution, there have been no significant adverse side > effects reported.  SinoFresh can also be used in conjunction with other > traditional medications without adverse reactions.  The total monthly dose of > CPC in SinoFresh is less than typical daily dose of an oral rinse product > containing CPC.  Its surface active properties and proven safety profile in > mucosal applications makes it an ideal agent for intranasal topical use.  The > intact SinoFresh product containing .05% CPC was tested in vitro against a > spectrum of bacteria and fungal organisms known to be present in rhinosinusitis > and was found to be both bactericidal and fungicidal, essentially on contact. > Swabs of the middle meatus taken before and after twice daily SinoFresh use has > show clearance of pathogens in as little as 4 days in initial studies.  A > visible reduction in nasal mucosal swelling accompanied this antimicorbial > response. > Organisms Killed by SinoFresh in vitro:* >        Bacteria > Haemophilus Influenzae > Moraxella Cattarrhalis > Streptotoccus Pyogenes > Staphlococcus Aureus > MRSA Species > Psudomonas Aeruginosa > Escherichia Coli >       Fungal Species-inhaled molds > Candida Albicans > Aspergillus Niger > Cladosporium Herbarum > Alternaria Alternata > Pennicillium Finiculosum > Fusarium Solani > Strachyboytris Chartarum > Who My Benefit From SinoFresh Use? > Patients with Chronic non-allergic nasal and sinus symptoms > Mold-allergic and sensitive patients > Fetid breath or nasal odor > Snoring > Travelers > People in close contact with the public > Patients with Chronic recurrent rhinosinusitis unresponsive to systemic > therapy** > *    USP Quantitative mini-kill time test – Nelson Laboratories, Salt Lake City > **  These patients may benefit from twice daily antiseptic cleansing of the > nose and sinuses.  Not intended as a treatment or proven preventive therapy of > any medical condition.

So does this mean we can just put some mouthwash (Scope which contains Cetylpyridinium Chloride) in a spray bottle and have the same affect? Then we don’t have to worry about the BKC or BKZ ingredient that so many on this board seem to react badly to.  A bottle of mouthwash sure is cheaper than a bottle of sinofresh.  Probably get that minty-fresh feel afterwards also.

Response:

On 30 Mar 2004 04:51:53 GMT, entcons…@aol.comnospam (ENTconsult) wrote: >I have been to the web site but couldn’t find any reference as to what is in >sino fresh. Anyonw know? >Murray Grossan, M.D. >http://www.ent-consult.com

According to http://www.sinofresh.com/content/clinicaloverview.aspx Clinical Overview What is SinoFresh? SinoFresh is a topical antiseptic nasal spray effective against the molds and bacteria that are most commonly associated with "Rhinosinusitis."  The need for an effective topical antimicrobial in nasal and sinus disease is well documented because, despite extended courses of systemic therapy, the spectrum of persistent bacteria and fungi in the nose and sinus is extensive.  It is the persistent extra mucosal colonization that allows these organisms to function as "living antigens," triggering lgG, lgE, and neutrophil medicated inflammatory reactions.  No other agent attacks the cause of the inflammatory response except for the dilutional effect of saline irrigation.  SinoFresh has been shown to kill these organisms, essentially on contact.  SinoFresh, 1-3 sprays twice daily, is used as a daily antiseptic nasal hygiene regiment in patients with chronic nasal and sinus symptoms and in patients who simply desire a refreshing cleansing of the accessible nasal and sinus mucosa. What is CPC? The active ingredient in SinoFresh is a surface active cationic antiseptic, Cetylpyridinium Chloride (CPC), with antimicrobial activity against bacteria, fungi, and viruses.  CPC has been used in oral rinse products for over fifty years and it`s safety has been documented extensively.  It has been formulated into topical nasal spray, along with moisturizers and mint aromatics, to be used as a nasal hygiene product.  In Intranasal safety studies to date, and national chain store distribution, there have been no significant adverse side effects reported.  SinoFresh can also be used in conjunction with other traditional medications without adverse reactions.  The total monthly dose of CPC in SinoFresh is less than typical daily dose of an oral rinse product containing CPC.  Its surface active properties and proven safety profile in mucosal applications makes it an ideal agent for intranasal topical use.  The intact SinoFresh product containing .05% CPC was tested in vitro against a spectrum of bacteria and fungal organisms known to be present in rhinosinusitis and was found to be both bactericidal and fungicidal, essentially on contact. Swabs of the middle meatus taken before and after twice daily SinoFresh use has show clearance of pathogens in as little as 4 days in initial studies.  A visible reduction in nasal mucosal swelling accompanied this antimicorbial response. Organisms Killed by SinoFresh in vitro:*        Bacteria Haemophilus Influenzae Moraxella Cattarrhalis Streptotoccus Pyogenes Staphlococcus Aureus MRSA Species Psudomonas Aeruginosa Escherichia Coli       Fungal Species-inhaled molds Candida Albicans Aspergillus Niger Cladosporium Herbarum Alternaria Alternata Pennicillium Finiculosum Fusarium Solani Strachyboytris Chartarum Who My Benefit From SinoFresh Use? Patients with Chronic non-allergic nasal and sinus symptoms Mold-allergic and sensitive patients Fetid breath or nasal odor Snoring Travelers People in close contact with the public Patients with Chronic recurrent rhinosinusitis unresponsive to systemic therapy** *    USP Quantitative mini-kill time test – Nelson Laboratories, Salt Lake City **  These patients may benefit from twice daily antiseptic cleansing of the nose and sinuses.  Not intended as a treatment or proven preventive therapy of any medical condition.

Response:

I have been to the web site but couldn’t find any reference as to what is in sino fresh. Anyonw know? Murray Grossan, M.D. http://www.ent-consult.com

Response:

Filed under: Rhinosinusitis

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