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Rich Murray: Stoll: Omega-3 fatty acids from flaxseed oil for bipolar disorder May 1999 3.28.1 rmforall

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Rich Murray: Stoll: Omega-3 fatty acids from flaxseed oil for bipolar disorder May 1999 3.28.1 rmforall March 28 2001   Hello Lloyd,  Why not try 4 Tbs flaxseed oil daily? Be sure to drink only distilled or deionized water, to reduce arsenic, lead, mercury,  fluoride, etc. 1943 Otowi Road   Santa Fe  NM 87505 505-986-9103 Prostaglandins Leukot Essent Fatty Acids 1999  May-Jun;60(5-6):329-37 Omega-3 fatty acids and bipolar disorder: a review. Stoll AL, Locke CA, Marangell LB, Severus WE Psychopharmacology Research Laboratory, McLean Hospital, Belmont, MA 02478, USA. The important role of the omega-3 fatty acids in the pathophysiology and treatment of bipolar disorder is now supported by a substantial body of indirect and direct evidence. This paper will describe the clinical and pharmacological features of bipolar disorder, review the available data regarding omega-3 fatty acids in bipolar disorder and provide recommendations for future research.   Publication Types: Review   Review, tutorial PMID: 10471117 Arch Gen Psychiatry 1999 May;56(5):407-12 Omega 3 fatty acids in bipolar disorder: a preliminary double-blind, placebo-controlled trial. Stoll AL, Severus WE, Freeman MP, Rueter S, Zboyan HA, Diamond E, Cress KK, Marangell LB Brigham and Women’s Hospital, Department of Psychiatry Harvard Medical School, Boston, BACKGROUND: Omega3 fatty acids may inhibit neuronal signal transduction pathways in a manner similar to that of lithium carbonate and valproate, 2 effective treatments for bipolar disorder. The present study was performed to examine whether omega3 fatty acids also exhibit mood-stabilizing properties in bipolar disorder. METHODS: A 4-month, double-blind, placebo-controlled study, comparing omega3 fatty acids (9.6 g/d) vs placebo (olive oil), in addition to usual treatment, in 30 patients with bipolar disorder. RESULTS: A Kaplan-Meier survival analysis of the cohort found that the omega3 fatty acid patient group had a significantly longer period of remission than the placebo group (P = .002; Mantel-Cox). In addition, for nearly every other outcome measure, the omega3 fatty acid group performed better than the placebo group. CONCLUSION: Omega3 fatty acids were well tolerated and improved the short-term course of illness in this preliminary study of patients with bipolar disorder. Publication Types: Clinical trial  Randomized controlled trial Comment in:   Arch Gen Psychiatry. 1999 May;56(5):413-6 Arch Gen Psychiatry. 2000 Jul;57(7):715 Arch Gen Psychiatry. 2000 Jul;57(7):716-7 PMID: 10232294 http://www.natmedpro.com/nmp/Bipolar.htm    many nutrients http://www.windsofchange.com/   The Winds of Change Bipolar Disorder Support Group The Winds of Change, Inc., P.O. Box 251453 Plano, TX 75025-1453, Phone: 972-312-7772 http://bipolar.about.com/health/bipolar/index.htm?rnk=c1&terms=bipolar with  Kimberly Bailey & Marcia Purse   extensive links & http://www.drmcdougall.com/science/depression.html   allergy to milk products  and high-gluten foods (like wheat, barley, and rye) alt.support.depression.manic.moderated– 13 Sep 2000 by LyndaNP – View Thread http://www.medscape.com/medscape/cno/1999/APA/Story.cfm?story_id=704 1999 American Psychiatric Association Annual Meeting Day 4 – May 20, 1999 General Guidelines and Intricacies in the Treatment of Bipolar Disorder Frederick K. Goodwin, MD    Writer: Tracey L. Irvin, MD Each psychiatrist should have a dietitian with whom they can consult on strategies for maintaining a diet low in simple carbohydrates in order to stabilize blood sugar. Patients with bipolar disorder tend to have unstable blood sugars, and many of the symptoms of hypoglycemia can be confused with those of the illness, or with side effects of the medication. In addition, patients should be encouraged to reduce their caffeine intake. Caffeine has the tendency to reduce the quality of sleep. This begins a vicious cycle in which decreased sleep quality leads to decreased daytime energy, leading to higher caffeine use. http://www.vegsource.com   excellent diet info http://www.notmilk.com       dairy toxicity http://www.litopia.com/jplant/   Jane Plant http://www.dorway.com       aspartame toxicity http://www.truthinlabeling.org/    MSG toxicity http://www.soyonlineservice.co.nz   soy toxicity http://www.thyroid-info.com   Mary J. Shomon http://www.npwa.freeserve.co.uk/    fluoride toxicity http://www.electric-words.com/junk/junkindex.html   junk science http://www.pbs.org/tradesecrets/transcript.html   Moyers on chemicals

Response:

Rich Murray: Stoll: Omega-3 fatty acids from flaxseed oil for bipolar disorder May 1999 3.28.1 rmforall

Dr. Stoll used fish oil, not flaxseed oil, in his double-blind trial for bipolar disorder. See web page OMEGA-3 FATTY ACIDS & BIPOLAR DISORDER Highlights of a Lecture by Andrew L. Stoll, M.D.,   Director, Psychopharmacology Research Laboratory, McLean Hospital June 9, 1999   http://www.mddaboston.org/lect060999.html A citation:    "In a double-blind study of 30 patients who were recently ill with bipolar    disorder, Dr. Stoll found omega-3 fatty acids from concentrated fish oil to    be an effective antidepressant and mood stabilizer.    [...]    Fish oil is currently the recommended source of omega-3.  Flaxseed oil and    perilla oil contain a different type of omega-3.  Several cases of hypomania    have occurred in people taking flaxseed oil, but the causes remain unclear." Other links: Omega-3 for Depression and Bipolar Suite101.com http://209.52.189.2/article.cfm/3694/48236 Omega-3 Fatty Acids Evaluated for Bipolar Disorder by Arline Kaplan Psychiatric Times  December 1999  Vol. XVI  Issue 12 http://www.mhsource.com/pt/p991211.html — Matti Narkia

Response:

I heard from someone who tried to use flax-seed oil as a mood stabiliser. He commented that it didn’t work for him.

– Hide quoted text — Show quoted text – Rich Rich Murray: Stoll: Omega-3 fatty acids from flaxseed oil for bipolar disorder May 1999 3.28.1 rmforall Dr. Stoll used fish oil, not flaxseed oil, in his double-blind trial for bipolar disorder. See web page OMEGA-3 FATTY ACIDS & BIPOLAR DISORDER Highlights of a Lecture by Andrew L. Stoll, M.D., Director, Psychopharmacology Research Laboratory, McLean Hospital June 9, 1999 http://www.mddaboston.org/lect060999.html A citation:    "In a double-blind study of 30 patients who were recently ill with bipolar    disorder, Dr. Stoll found omega-3 fatty acids from concentrated fish oil to    be an effective antidepressant and mood stabilizer.    [...]    Fish oil is currently the recommended source of omega-3.  Flaxseed oil and    perilla oil contain a different type of omega-3.  Several cases of hypomania    have occurred in people taking flaxseed oil, but the causes remain unclear." Other links: Omega-3 for Depression and Bipolar Suite101.com http://209.52.189.2/article.cfm/3694/48236 Omega-3 Fatty Acids Evaluated for Bipolar Disorder by Arline Kaplan Psychiatric Times  December 1999  Vol. XVI  Issue 12 http://www.mhsource.com/pt/p991211.html — Matti Narkia

Response:

It really does take a Total System Chemistry Analysis (OVER TIME) to pull these stunts off. We are getting closer to understanding the variables. But that is all for the next decade or so. Sorry, rmg

I heard from someone who tried to use flax-seed oil as a mood stabiliser. He commented that it didn’t work for him.

Response:

Filed under: Pathophysiology

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